Son Heung-Min pulled a goal back late in the second half for the visitors but it did little to alter the result.
Saka squared a ball in the box on 12 minutes which Smith Rowe ran onto and slotted it into the net from 10 yards out.
The Arsenal captain played a one-two with Smith Rowe before receiving the ball back and hitting it past Hugo Lloris.
The third goal of the half came on 34 minutes when Saka found space and attempted to play a pass into Aubameyang. However, Harry Kane‘s missed tackle granted the ball back to the young England international who put it in the net.
Arsenal went into half time 3-0 up, the first time they’ve held such a lead against a top six team since 2016.
Tottenham pressed Arsenal harder in the second half but it wasn’t until 79 minutes that they managed to register a goal.
Sergio Reguilon drove a low hard ball into the box which Son blasted into the net.